In every situation and every environment, you really have to use the carpet cleaning equipment that is suitable for it. With the presence of the different types of carpet cleaning equipment, getting what would suit your needs seem to be hard. When purchasing the carpet cleaning equipment, be certain if the cleaning equipment will be able to manage the task that you will be doing. It must have the capacity to operate and accomplish your task.
In terms of buying a carpet cleaning equipment, many buyers would ask these questions.
* What are the carpet cleaning equipment that you have for sale as of now?
Usually, the common carpet cleaning equipment that you have within the day is the truck mounts. They handle heavy duty cleaning jobs.Other choices that you also have are the walk in behind carpet extractors, portable carpet cleaners and then encapsulation carpet cleaners. Of your business, the latter three carpet cleaning equipment would best serve.
* Other than cleaning carpets, what are the other function of carpet cleaning equipment?
Well yes. There are some carpet cleaning equipment that can also be used in terms of cleaning hard surfaces, tiles, grout or even upholstery. One example is the truck mount.It would also be possible for you to clean the upholstery through the walk behind carpet extractors. Different kinds of surfaces can also be stripped, waxed, polished, and then cleaned through the encapsulation carpet cleaners.
* What Carpet Cleaner Size Should I buy?
There are some things that you have to consider in terms of getting the size of the carpet cleaning equipment that you need. Look at the space that you will be cleaning and will be using the carpet cleaning equipment for. Use the walk behind carpet instructor once you will be cleaning large open areas or a number of areas. This would fit very well for such purpose. Make use of the encapsulation carpet cleaners if you also deal with large areas or even long hallways where many people will pass. It is important however that you clean them with the absence of a lot of moisture.In terms of smaller areas like classrooms or small offices, cleaning can be done through the use of portable carpet cleaners.
* What can we expect from an Encapsulation carpet cleaner?
The encapsulation carpet cleaners are very ideal for business which currently have a variety of surfaces to clean. It can help cleaning the hardwood floors, carpets, tiles and etc. Commonly, there are many schools, hospitals and departments stores that are using this kind of carpet cleaning equipment. This kind of cleaning equipment would be able to handle all the carpet cleaning for all areas. This encapsulation carpet cleaner would make cleaning possible through the use of a very little moisture. Waxing, Stripping, and Polishing will be handled at the same time.
The moment you search carpet cleaning machines into Yahoo, do you discover the thing you need?
AP - Two signs of trouble elsewhere in the world pushed U.S. stocks lower: slowing economic growth in China and a possible hitch in a deal to get Greece its bailout money.
The loss of a protein makes 'jump' the tumor to the lymph nodePublic release date: 6-Mar-2012 [ | E-mail | Share ]
Contact: Arantxa Mena comunicacio@idibell.cat IDIBELL-Bellvitge Biomedical Research Institute
Discovered a mechanism explaining how tumor cells spread to nearby organs and structures, initiating metastasis
Metastasis is responsible for 90% of deaths in patients with cancer. Understanding the mechanisms responsible for this process is one of the top goals of cancer research. The metastatic process involves a series of steps chained where the primary tumour invades surrounding tissues and ends spreading throughout the body. Ones of the first tissues undergoing metastasis are the lymph nodes surrounding the tumour.
A study, led by the researcher at the Bellvitge Biomedical Research Institute (IDIBELL), Manel Esteller, published in the Journal of Pathology, had identified a mechanism that explains how cancer cells escape from its original site to the lymph nodes. Investigations have uncovered that metastatic tumour cells that grow in the lymph nodes of patients with melanoma and head and neck tumours lose the activity of a protein called cadherin-11.
The normal function of this protein is to act as the anchor of a ship to fix the cells in a specific position and prevent movement. Inactivation of cadherin-11 gene causes the loss of this fixation and tumour cells "jump" to neighboring organs and structures, such as lymph nodes.
The study is an example of translational and multidisciplinary research, involving basic research laboratories, the medical oncology service at the Catalan Institute of Oncology (ICO) and the Pathology Service of the Bellvitge University Hospital.
The study coordinated by the director of the Cancer Epigenetics and Biology Program at IDIBELL, ICREA researcher and professor at the University of Barcelona, Manel Esteller, also proposes that the process can be reversed because, in models in vitro and in vivo, the recovery of protein activity cadherin-11 caused a slowing of tumour growth and decreased ability to generate metastases.
This possibility needs to be studied in international clinical trials, but it is a promising starting point in studying the biology of metastasis and how to act therapeutically in this area.
###
Who we are
Bellvitge Institute for Biomedical Research (IDIBELL) is a research centre created in 2004 with the participation of the Bellvitge University Hospital, the Catalan Institute of Oncology, and the University of Barcelona. IDIBELL is integrated in Biopol'H, the health and scientific park of l'Hospitalet de Llobregat-Barcelona.
Article's reference
Carmona FJ, Villanueva A, Vidal A, Muoz C, Puertas S, Penin RM, Gom M, Lujambio A, Piulats JM, Mesa R, Snchez-Cspedes M, Mans M, Condom E, Eccles SA, Esteller M. Epigenetic Disruption of Cadherin-11 in Human Cancer Metastasis. The Journal of Pathology. 2012 Feb 28. doi: 10.1002/path.4011
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
The loss of a protein makes 'jump' the tumor to the lymph nodePublic release date: 6-Mar-2012 [ | E-mail | Share ]
Contact: Arantxa Mena comunicacio@idibell.cat IDIBELL-Bellvitge Biomedical Research Institute
Discovered a mechanism explaining how tumor cells spread to nearby organs and structures, initiating metastasis
Metastasis is responsible for 90% of deaths in patients with cancer. Understanding the mechanisms responsible for this process is one of the top goals of cancer research. The metastatic process involves a series of steps chained where the primary tumour invades surrounding tissues and ends spreading throughout the body. Ones of the first tissues undergoing metastasis are the lymph nodes surrounding the tumour.
A study, led by the researcher at the Bellvitge Biomedical Research Institute (IDIBELL), Manel Esteller, published in the Journal of Pathology, had identified a mechanism that explains how cancer cells escape from its original site to the lymph nodes. Investigations have uncovered that metastatic tumour cells that grow in the lymph nodes of patients with melanoma and head and neck tumours lose the activity of a protein called cadherin-11.
The normal function of this protein is to act as the anchor of a ship to fix the cells in a specific position and prevent movement. Inactivation of cadherin-11 gene causes the loss of this fixation and tumour cells "jump" to neighboring organs and structures, such as lymph nodes.
The study is an example of translational and multidisciplinary research, involving basic research laboratories, the medical oncology service at the Catalan Institute of Oncology (ICO) and the Pathology Service of the Bellvitge University Hospital.
The study coordinated by the director of the Cancer Epigenetics and Biology Program at IDIBELL, ICREA researcher and professor at the University of Barcelona, Manel Esteller, also proposes that the process can be reversed because, in models in vitro and in vivo, the recovery of protein activity cadherin-11 caused a slowing of tumour growth and decreased ability to generate metastases.
This possibility needs to be studied in international clinical trials, but it is a promising starting point in studying the biology of metastasis and how to act therapeutically in this area.
###
Who we are
Bellvitge Institute for Biomedical Research (IDIBELL) is a research centre created in 2004 with the participation of the Bellvitge University Hospital, the Catalan Institute of Oncology, and the University of Barcelona. IDIBELL is integrated in Biopol'H, the health and scientific park of l'Hospitalet de Llobregat-Barcelona.
Article's reference
Carmona FJ, Villanueva A, Vidal A, Muoz C, Puertas S, Penin RM, Gom M, Lujambio A, Piulats JM, Mesa R, Snchez-Cspedes M, Mans M, Condom E, Eccles SA, Esteller M. Epigenetic Disruption of Cadherin-11 in Human Cancer Metastasis. The Journal of Pathology. 2012 Feb 28. doi: 10.1002/path.4011
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Business communication h?? evolved greatly throughout centuries ?nd continues t? change ?t f??t speeds. Relaying messages ?n a professional setting ?r? vital t? th? production ?nd life ?f ?n organization. Business communication plays a role ?n day-t?-day activities ?t work, business trends m?? b? observed, ?nd message types m?? vary ?? a result fr?m business communication trends.
??????????? Communication ??n b? verbal, non-verbal, ?nd written. Verbal communication ?n a business setting ?? th? m??t personal ?? ?t displays inflections, dialects, ?nd diction. Verbal communication ?? th? first communication form ?f each day f?r m? ?t th? office. Wh?n I enter ?nt? th? five ?t?r? corporate building ?n th? a.m., potential communication ?? always anticipated. Elevator talk, passive greetings, ?nd non-verbal communication ?r? d???l???d within th? business building. One entered ?nt? th? office, a greeting ?? m?d? t? th? corporate secretary ?? I walk t? m? executive office w?th a view. Late emails ?r? ?n?w?r?d ?nd voicemails ?r? returned ?ft?r checking th? fax machine f?r submissions wh?l? sipping ?n a cup ?f Starbucks coffee. M? day h?? begun. Business communication plays a vital role ?n m? day-t? day activities ?t work. Within th? first fifteen minutes ?f m? work day, I h??? potentially communicated verbally, non- verbally, through th? telephone, fax, ?nd through electronic mail (email). Business communication allows m? t? manage m? work day more efficiently. Faxed statements fr?m local entities prevent lengthy wait times f?r postal mail shipments. Email allows m? t? send documents, receive documents, ?nd relay messages ?t th? click ?f a button. Additionally email ??n send bulk memos t? inform a large audience ?f procedural updates ?nd ?th?r applicable data.? Once ?n email ?? ?t?rt?d, a simple r??l? ?? required t? continue communicating. Th? telephone ?? a wonderful way t? speak w?th clients, candidates, ?nd ?th?r business t? business (b2b) entities. Th? efficiency ?f business communications ?? th? greatest asset.
??????????? Business trends ?r? generally regional ?nd standardized. Wh?n technology ?? released, m??t business entities adapt. In business, I h??? noticed a growing ??? f?r PDA cellular devices ?nd laptop computers f?r sales representatives ?n m??t major industries. F?r th? small business, fax machines ?r? becoming optional w?th th? ability ?nd growing demand f?r scanners ?nd email attachments. Interoffice mail ?? ?l?? a n?w trend f?r modern corporations wh?r? individual postage ?? n?t necessary ?nd mailstops replace th? physical address ?n a package. Oth?r business communication trends ?r? ?n relation t? th? business-client relationship. Th? social networking trend h?? dominated th? business industry ?? millions ?f businesses ?nd business persons ?r??t? ?n online profile ?n hopes ?f building th??r brand ?nd offering heightened presence. Th? original trend w?? business cards, th?n a website, now a social networking profile. Business cards h??? ?l?? changed faces ?? th? standard business card ?? seemingly frowned upon ?nd m??t b? updated w?th innovative design ?nd unique construction including materials.? Business marketing ?? th? primary source f?r business communication wh?l? building a brand ?nd h?? ?l?? evolved. Today, vehicles ??n b? wrapped ?n ?n advertisement t? b? viewed during normal driving situations. Direct mail campaigns ?r? ?l?? a growing trend b? comparison t? th? 1950?s wh?r? junk mail w?? simply unheard ?f. ??
??????????? ?Th? four levels ?f information richness ?n business communication ?r? ?? follows: face-t?-face communication, spoken communication electronically transmitted (telephone ?r voicemail), personally addressed written communication (personal messages), ?nd impersonal written communication (impersonal messages)? (Consador, 2010). Th? aforementioned levels ?r? ?l?? message types th?t result fr?m business trends ?n wh??h m??t ?ll business communications w?ll result. F?r example, th? trend ?f PDA cellular devices ?? a form ?f business communication w?ll result ?n telephone communication, email, instant message, ?r text message.
??????????? T? communicate within business, ?t ?? ?m??rt?nt t? observe ethical standards. Corporations ?nd ?th?r business industry organizations compete f?r highest profits ?r l?rg??t market shares wh??h h?? weighed management down w?th a heavy burden t? meet ?r exceed financial projections implemented b? ?n organization?s intelligence. Wh?n a manager operates w?th th? trait ?f applying clear goals ?nd direction, success m?? abound through th? clarity ?f expectations. Clear goals ?nd direction ?? always communicated ?nd therefore highly regarded t? th? success ?f th? organization itself. Communication ?? h?w business transpires. Effective management occurs wh?n management ?nd th??r subordinates operate within productive communication relationships th?t produce a desired ?r exceeded outcome.
Consador, Kat. (2010). Four Types ?f Business Communication. Retrieved December 13, 2010 ?? fr?m, http://www.ehow.com/about_5447910_four-types-business-communication.html
Mobile technology advances are dramatically increasing the intensity of competition broadly online and offline. The technological convenience of using a smart phone, tablet etc. rather than a card or cash to pay for goods and services, wherever one may be, is igniting a competitive free-for-all.
That's because the technological shift to devices rather than cards creates a huge potential competitive opportunity for most everyone in the competitive ecosystem to potentially disintermediate other industries -- i.e.Wrest control of the customer relationship, customers' private information, interests and metadata, and also the bundling of marketing coupons and promotions, in markets with transactions in the trillions of dollars annually.
Activists and regulators who fear a potential new communications "opoly" lurking around every corner -- in need of preemptive government intervention to protect consumers from the convenience, savings and benefits of a highly-competitive marketplace -- need to take a breath, enjoy, and get out of the way of this amazing technological convergence and innovation over mobile payments.
As I described in my forward-looking competition presentation: "The Metamorphosis of Communications Competition Driven By Broadband, Internet, and Cloud Computing Technologies," technology innovations are driving a huge increase in competition as everyone is getting into everyone else's business. The consumer is the big beneficiary of this technology-driven new competition. And mobile payment technology is but one of many big technology shifts in communications and technology that will further increase competition going forward.
The Competitive Clash of Multiple Industry Titans
As the Wall Street Journal recently spotlighted, "The [mobile payment] race pits the retailers against banks, credit-card networks, telecommunications firms and technology companies."
Retailers: The latest news is that Walmart, Target, and other big-box stores, and drugstores, vending companies and fast-food restaurants, are working together to develop a merchant-friendly mobile payments system. Per the WSJ, this loose consortium represents upwards of $1.38 trillion in revenue. The very existence of this unusual sector-uniting alliance of competing merchants heralds how potentially disruptive mobile payments could be long term and how much merchants want to ensure that mobile payment technology and standards don't disintermediate them from their customers, leaving them with the cost of bricks and mortar, and without the mobile/online upside of getting customers to spend fully with them at their expensive-to-maintain locations.
Google Wallet-Motorola-MasterCard-Sprint: Per Gigaom: "Google Wallet has secured some very important partnerships,locking up deals with the four main payment networks- Visa, MasterCard, American Express and Discover andhardware manufacturers?HTC, LG, Motorola Mobility, RIM, Samsung Mobile and Sony." Unfortunately Google Wallet also stumbled badly in its rush to be first to market with near field technology (NFC = two-inch communication range technology). Security firms discovered two easy ways to break into Google Wallet that allowed a hacker to steal the user's money in the Google Wallet, prompting Google to suspend use of prepaid cards on Google Wallet "to prevent painfully easy attack" until it could be fixed. Google now says these vulnerabilities have been fixed, but the question remains why did they rush to market without adequate security vetting to protect users funds entrusted to Google?
AT&T-Verizon-T-Mobile:Reportedly, the Isis Mobile Wallet from three of the four largest wireless providers Verizon, AT&T, and T-Mobile will work with Chase Bank, Capitol One and Barclays, and will enable credit, debit and prepaid cards to be loaded into the Isis mobile wallet. These financial institutions have card relationships with 100m American consumers.
Apple: Apple may prove to be the big sleeper mobile payments competitor here, that media coverage to date may be missing. Reports indicate Apple, the $500b technology manufacturing leader, is poised to integrate near-field-communications (NFC) into future iPhones and iPads. This is significant because most people do not realize Apple starts with 225 million credit card numbers from its iTunes service. Moreover, most would be surprised to learn that Apple's 358 retail stores have an average-revenue-per-store that is larger than every retailer other than Walmart.
Ebay-Paypal:Reportedly, Paypal, the dominant online payment provider, has plans to offer an in-store mobile payment system that will work differently than others; it will work by a user keying in a phone number and a PIN to make a payment.
Microsoft-Nokia: Microsoft, the leader in personal and office software is reportedly working with Nokia to incorporate a mobile payments capability into its smart phone software to enable purchases with a swipe of the device.
Amazon: Amazon began offering a Mobile Payments Service in 2009, which included APIs for developers to allow users to use Amazon's "1 Click" checkout, which enables users to purchase Amazon goods from their mobile device using their credit card stored at Amazon.
In sum, competition over mobile payments is increasing, providing strong evidence that near field communications, broadband, Internet and cloud computing technologies are igniting a competitive free for all. This is just one of many areas where technology is increasing communications competition to the great benefit of the consumer.
Have to you perform computer system online games or online video video games?
Article by Peero Merkanana
Taking part in game titles arrives normally to us considering that even as young people we have performed an array of games, both with buddies, on printed card boards, with computer systems or even playing cards. Gaming is deeply rooted in history as perfectly, as male, at any time due to the fact he grew consciousness, wanted a way to pass time and entertain himself. But these times, gaming means only a single matter. Video games normally play in a number of platforms. The two principal ones are gaming consoles like the Xbox and PS3 and gaming computers that are developed to consider the punishment that fashionable games toss on them. The battle rages on while, for a correct gamer, what comes out on very best? Gaming personal computers or gaming consoles? There are a whole lot of matters to look into the following.
A single, gaming PCs are ordinarily dissed considering that of the numerous viruses and complications that developers have had with the platform. Gaming consoles have the historical past of remaining criticized for remaining way too rigid, with out the capacity to turn into upgraded when new solutions will come up. There are a several facets of the two that we want to focus on the following in this piece to give as fair a comparison as potential.
Earliest, let?s speak about connectivity and interactive features. 1 could presume that gaming computer systems have the higher hand in this discussion, staying by default, connected to the online world and with a whole lot significantly more networking capabilities and gaming rooms, supplying results to plenty of Massively Multiplayer Function Playing Games or MMORPGs more than the decades. But then, why are a ton of the far more successful games in the new 12 months on well-known gaming consoles and supply the power for single unit multiplayer video games? Selecting up a controller and battling your buddy facet to side beats battling a faceless player on the other side of the world, each individual time. And moreover, gaming consoles are now considerably more linked about the web-based and supply the exact same above the internet competitions as personal computers do.
Now permit us chat about electrical power. Simply because gaming consoles usually aren?t upgraded, meaning you actually cannot include much to it soon after you pay for it, companies make positive that they launch a little something that packs as considerably electricity as it can to deal with upcoming games that have more computing punch.
This is in which gaming computers have the gain. Since they are exceptionally customizable, the energy of a device is expandable dependent on its owner?s hard earned cash and specialized capabilities. But as the Nintendo Wii has established, players, however traditionally fond of higher technologies and more desirable graphics, can also be swayed by gameplay and plot. The Wii can easily not compete with the electrical power of a reason-crafted gaming laptop computer or its rivals the PS3 and Xbox, but it has liked additional commercial accomplishment extra than any of the other three we have talked about.